The rate of environmental change drives adaptation to an antibiotic sink
نویسندگان
چکیده
منابع مشابه
Environmental change drives accelerated adaptation through stimulated copy number variation
Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can interfere with replication fork progression and stability, leading to increased mutation rates at h...
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ژورنال
عنوان ژورنال: Journal of Evolutionary Biology
سال: 2008
ISSN: 1010-061X,1420-9101
DOI: 10.1111/j.1420-9101.2008.01596.x